CVD is a major public health problem. High blood pressure and circulating LDL levels are major risk factors for promoting atherosclerosis, ischemic heart disease or stroke. PUFA act as substrates for eicosanoid formation. Eicosanoids formed from omega 3 are anti- inflammatory in nature and possess cardioprotective effects through various mechanisms with DHA being most potent followed by EPA and ALA in preventing cardiovascular disease. But conversion of ALA to EPA and DHA is less efficient. So, walnuts and flaxseed being very good source of ALA should be included in the diet with dose depending on the severity of disease. Along with this, consumption of fatty fish at least 2 servings per week or fish oil supplementation is necessary for reducing the risk of cardiovascular disease.