Objectives: To evaluate patients with multi-level thoraco-lumbar spinal injuries who had pedicle screw fixation. Subjects and methods: Observational study on 53 patients with multilevel thoraco-lumbar spinal injuries admitted to Danang Hospital from March 2014 to May 2018 who underwent pedicle screw fixation. Results and conclusions: Male/female ratio was 4.88/1, mean age was 37 years old. Common types of injuries were work-related (39.62%) and fall (39.62%). Burst spine fractures were 71.69%, dislocation spine fractures were 17%.