The fertility rate in Rwanda decreased from 6.1 in 2005 to 4.6 in 2010 and to 4.2 in 2015. Widespread use of contraceptives has played a main role in this decrease. A cross sectional study was conducted on knowledge, attitude and practices of family planning methods on 426 pregnant women attending antenatal clinic in six health facilities in Rwanda. To assess the knowledge, attitude and practice of family planning methods and to determine the past and future intent of post-partum contraceptive use and factors associated with discontinuation of family planning methods among pregnant women attending antenatal clinic in Rwanda.